MOTS-c

Research reagent · CAS 1627580-64-6 · Lyophilized vial

Product name	MOTS-c
CAS number	1627580-64-6
Sequence	MRWQEMGYIFYPRKLR
Molecular formula	C101H152N28O22S2
Molecular weight	~2174.6 Da
Form	Lyophilized vial
Storage	Sealed, dry, −20 °C, protect from light
Salt	Stated on lot COA

Presentations

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40 mg	Coming soon	Request quote

Overview

MOTS-c is a 16-residue mitochondrial-derived peptide encoded within the MT-RNR1 gene. It is studied in AMPK-related signaling models and mitochondrial-nuclear communication pathways. The peptide has been used in metabolic-stress assays to explore how mitochondrially encoded peptides participate in cellular energy sensing. Methionine residues in the sequence can undergo oxidation, which may shift the observed mass; researchers should confirm identity by mass spectrometry. The catalog item is a research reagent for in-vitro laboratory use.

Research context

AMPK-related signaling models
Mitochondrial-nuclear signaling pathways
Metabolic-stress assays in cell culture
Insulin-signaling pathway research
Methionine oxidation and mass-shift confirmation by MS

Documentation

A supplier Certificate of Analysis (COA) is a starting point. Released lots are verified by an independent U.S. laboratory:

Identity by LC-MS
HPLC purity
Peptide content
Salt composition
Endotoxin
Sterility when offered for sterile in-vitro work
Metals and water when on the panel

Certificates appear here when a lot is verified.

Research use only. Not a drug, pharmacy, or 503A/503B compounding facility. Not for human or veterinary use. This product is not intended to diagnose, treat, cure, or prevent any disease.

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